TABLE 1.

Demographic and Clinical Characteristics of North Carolina Patients with E-cigarette, or Vaping, Product Use Associated Lung Injury (N = 78)

Characteristicn/N%
Age (years)
    <1814/7818
    18–2426/7833
    25–3422/7828
    35–449/7812
    ≥457/789
    Age, median (IQR)24 (19, 34) 
Sex
    Male49/7863
    Female29/7837
Race/Ethnicity
    White, non-Hispanic50/5985
    Black, non-Hispanic2/593
    Other, non-Hispanic1/592
    Hispanic6/5910
Past Medical History
    Respiratory disease12/7815
    Heart disease4/785
    Anxiety19/7824
    Depression13/7817
Hospital Course
    Hospital admission75/7896
    Intensive care unit admission32/7841
    Respiratory support57/7873
      Noninvasive respiratory support45/7858
      Mechanical ventilation12/7815
    Symptom onset to hospitalization, days, median (IQR)a6 (4, 9) 
    Hospital admission to discharge, days, median (IQR)a5 (4, 8) 
    Prior care before hospital admissiona,b44/7559
Symptoms
    Respiratory75/7896
      Shortness of breath66/7885
      Any chest pain27/7835
      Pleuritic chest painc10/7713
      Cough70/7890
      Hemoptysis6/788
    Gastrointestinal63/7881
      Nausea57/7873
      Vomiting56/7872
      Diarrheac29/7738
      Abdominal pain17/7822
    Constitutional72/7892
      Subjective fever68/7887
      Chills37/7847
      Weight loss16/7821
      Fatigue or malaise31/7840
    Headache31/7840
Vital Signs at Presentation
    Temperature ≥38°C16/6226
    Heart rate >100 beats/minute39/6164
    Respiratory rate >20 breaths/minute28/6146
    Oxygen saturation <90%13/6221
Laboratory Results
    White cell count >11,000/mmc and neutrophils >80%27/4264
    Creatinine, mg/dL, median (IQR)0.79 (0.60, 0.90) 
Chest Imaging Findingsd
    Abnormal chest computed tomography70/70100
    Pleural effusion8/7011
    Pneumomediastinum3/704
    Pneumothorax2/703
Treatment
    Steroids63/7881
    Antibiotics75/7896
  • Note. IQR = interquartile range

  • a Among patients admitted to hospital

  • b Received care at another location (e.g. urgent care or in outpatient setting) for lung injury before admission

  • c Data missing for one patient

  • d Among patients who had chest computed tomography