Diseases and Conditions Reportable in North Carolina Within a Specific Timeframe

Physicians must report these diseases and conditions to the county local health department, according to the North Carolina Administrative Code: 10A NCAC 41A.0101 Reportable Diseases and Conditions. Contact information for local health departments can be accessed at If physicians are unable to contact their local health department, they can call the 24/7 pager for NCDHHS, Communicable Disease Branch (919) 733-3419.
BotulismNovel coronavirus infectionSmallpox
Hemorrhagic fever virusNovel influenza infectionTularemia
24 hoursAcquired immunodeficiency virus (AIDS)Hemolytic-uremic syndrome (HUS)Salmonellosis
Campylobacter infectionHepatitis ASevere acute respiratory syndrome (SARS)
Candida aurisHepatitis BShigellosis
Carbapenem-resistant Enterobacteriaceae (CRE)Human immunodeficiency virus (HIV) infectionStaphylococcus aureus with reduced susceptibility to vancomycin
ChancroidInfluenza virus infection causing death
Chikungunya virus infectionListeriosisSyphilisb
CholeraMeningococcal disease, invasiveTuberculosis
CryptosporidiosisMiddle East Respiratory syndrome (MERS)Typhoid fever, acute (Salmonella typhi)
DiphtheriaNovel coronavirus infection causing deathVaricella (chickenpox)
Escherichia coli, shiga toxin-producing infectionOphthalmia neonatoriumVibrio infectionc
Foodborne diseaseaParalytic poliomyelitisVibrio vulnificus
GonorrheaPertussis (whooping cough)Zika virus
Granuloma inguinaleRabies, human
Haemophilus influenzae, invasive diseaseRubella
7 daysAcute flaccid myelitisInterferon-gamma release assay (IGRA)Q fever
AnaplasmosisLegionellosisRubella congenital syndrome
Arborviral infection, invasivedLeprosySpotted fever rickettsiosis (including RMSF)
BabesiosisLeptospirosisStreptococcal infection, Group A, invasive
BrucellosisLyme diseaseTetanus
Chlamydial infectionLymphogranuloma venereumToxic shock syndromee
Creutzfeldt-Jakob diseaseMalariaTrichinosis
DengueMeningitis, pneumococcalTyphoid carriage (Salmonella typhi)
EhrlichiosisMumpsTyphus, epidemic (louse-borne)
Hantavirus infectionNongonococcal urethritisYellow fever
Hepatitis B carriage or perinatally-acquiredPelvic inflammatory disease
Hepatitis C, acutePsittacosis
  • Note. For diseases and conditions required to be reported within 24 hours, the initial report shall be made by telephone to the local health department, and the written disease report be made within 7 days. The reporting rules and disease report forms can be accessed at:

  • a including Clostridium perfringens, staphylococcal, Bacillus cereus, and other and unknown causes

  • b primary, secondary, early latent, late latent, late with clinical manifestations, congenital

  • c other than cholera & vulnificus

  • d WNV, LAC, EEE, other, unspecified

  • e non-streptococcal or streptococcal

  • Source. Adapted from