In 2022, the North Carolina Medical Journal will illuminate the challenges and opportunities North Carolinians face as we work toward ambitious health goals. The third issue of the year focuses on policy, programs, data, and outcomes related to the uninsurance rate, primary care clinician ratio, access to early prenatal care, and suicide rate in North Carolina. Read the articles in this issue to learn more about the Healthy NC 2030 initiative, and see how people across NC are moving its work forward.